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Big 12 Football Week 6: Predictions, Picks and Previews for Every Game

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Week 6 of the Big 12 football season has arrived, and the conference race is beginning to take shape. Several teams face pivotal matchups that could have major implications in the chase for a spot in the Big 12 Championship Game, including a massive showdown between BYU and Iowa State in Provo and a critical matchup between Kansas State and Texas Tech in Manhattan. Elsewhere, Oklahoma State looks to remain among the league’s top contenders, Cincinnati aims to continue its surprising rise, and teams like Arizona, Baylor and Utah have opportunities to strengthen their position in the conference standings. Here are our predictions, picks and previews for every Big 12 game in Week 6.

Iowa State at BYU

One of the biggest games of the weekend takes place in Provo as Iowa State and BYU meet in a matchup with major Big 12 implications. The Cougars are looking to stay unbeaten in conference play, while the Cyclones have an opportunity to earn a statement road win against one of the league’s top defenses.

Iowa State vs. BYU Prediction, Pick and Odds for Week 6


UCF at Oklahoma State

Oklahoma State returns home after another impressive offensive performance, while UCF heads to Stillwater looking to knock off one of the conference’s most explosive teams. The Knights have shown flashes this season and will have a chance to prove themselves against a Cowboys team with Big 12 title aspirations.

UCF vs. Oklahoma State Prediction, Pick and Odds for Week 6


Arizona at West Virginia

Arizona travels to Morgantown for a matchup featuring two teams searching for momentum in conference play. The Wildcats continue to rely on one of the Big 12’s top quarterbacks, while West Virginia hopes to defend home field and keep pace in the conference race.

Arizona vs. West Virginia Prediction, Pick and Odds for Week 6


Houston at Kansas State

It doesn’t get much bigger than this in the Big 12. Both Texas Tech and Kansas State enter Week 6 with their eyes firmly set on Arlington, making this one of the most important conference games of the weekend. With talented quarterbacks on both sides and little room for error, the stakes are high in Manhattan.

Houston vs. Kansas State Prediction, Pick and Odds for Week 6


Kansas at Utah

Kansas heads west for one of its toughest tests of the season against Utah. The Utes have established themselves as one of the conference’s top teams, while the Jayhawks are looking to pick up a quality road win and gain traction in Big 12 play.

Kansas vs. Utah Prediction, Pick and Odds for Week 6


Hawaii at Arizona State

Arizona State is home for what is hopefully a get-right game against 1-4 Hawaii. The Sun Devils lost last week to Baylor 55-19.

Hawaii vs. Arizona State Prediction, Pick and Odds for Week 6

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