Big 12 News

Opening Lines Released for Week 2 of 2021 Big 12 Football Season

NCAA Football: Texas Christian at Baylor

With Week 1 of the Big 12 football season in the books, we’re already looking ahead to Week 2, where there are several intriguing match ups in the league. This includes a trip to Ames, Iowa from College GameDay where Iowa takes on Iowa State.

But there are plenty of other intriguing Big 12 games on the schedule in Week 2 and we’ve got the betting lines for each of the games.

Reminder: FBS vs. FCS lines may not come out, and if they do, don’t appear until the end of the week.


Big 12 Football Week 2 Opening Lines

Kansas +27.5 at Coastal Carolina

Iowa State -3.5 vs. Iowa

Oklahoma State -12.5 vs. Tulsa

Texas -6.5 at Arkansas

TCU -9.5 vs. Cal

The other five Big 12 teams are all playing FCS opponent this week. So the Big 12 will be favored in nine of its 10 games this week, including all three against Power 5 opponents. This is a good sign for the Big 12, which was also the only Power 5 Conference who did not have a loss to a Group of 5 or FCS team this past weekend. That also means there is plenty of pressure heading into Week 2.

Our Big 12 picks went 3-3 against the spread last week, as we look to build on that record in Week 2. The picks are brought to you by,, where with our promo code “BIG12” you double your first deposit!

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