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Big 12 Football Week 7 Predictions and Picks

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Week 7 of the 2026 Big 12 football season is here, and Saturday brings one of the conference’s best slates of the season. The biggest game comes in Provo, where No. 8 BYU hosts No. 2 Notre Dame with College GameDay in town and the Cougars looking for a massive win for both their College Football Playoff hopes and the Big 12. But that’s hardly the only game with major implications.

No. 18 Oklahoma State travels to No. 20 Houston for a ranked conference showdown, No. 10 Texas Tech puts its undefeated record on the line against Arizona State, and the Sunflower Showdown between Kansas and Kansas State features two teams desperate for their first Big 12 victory.

There are seven games involving Big 12 teams on Saturday, so let’s get to our Week 7 predictions and picks.

Cincinnati at West Virginia

Saturday, 12:00 p.m. ET | TNT/truTV

Cincinnati heads to Morgantown looking to get back on track in Big 12 play, while West Virginia desperately needs a conference win after an 0-3 start. The Mountaineers have been able to score points, but their defense has become one of the biggest concerns in the Big 12.

Cincinnati vs. West Virginia Prediction, Pick and Preview

Kansas at Kansas State

Saturday, 12:00 p.m. ET | FS1

The Sunflower Showdown arrives with both programs in desperate need of a win. Kansas State has dominated this rivalry for nearly two decades, but the Wildcats have struggled defensively this season, giving Kansas an opportunity to finally end its long losing streak against K-State.

Kansas vs. Kansas State Prediction, Pick and Preview

Arizona State at No. 10 Texas Tech

Saturday, 3:30 p.m. ET | FOX

Texas Tech returns from its bye week undefeated and firmly in the Big 12 Championship race. Arizona State got back in the win column against Hawaii, but a trip to Lubbock represents a major step up in competition for the Sun Devils.

Arizona State vs. Texas Tech Prediction, Pick and Preview

TCU at Baylor

Saturday, 7:00 p.m. ET | FS1

It’s time for the Revivalry in Waco. Baylor enters the weekend undefeated in Big 12 play, while TCU is trying to turn its season around after dropping its first two conference games. Rivalry games can get weird, but the Horned Frogs badly need this one to keep their season from slipping away.

TCU vs. Baylor Prediction, Pick and Preview

No. 2 Notre Dame at No. 8 BYU

Saturday, 7:30 p.m. ET | ABC

This is the headliner.

College GameDay is in Provo as undefeated BYU gets a massive opportunity against No. 2 Notre Dame. The Cougars are double-digit underdogs despite having one of the best defenses in the country, and I believe this matchup is much closer than the point spread suggests.

In fact, I’m calling for the upset.

Notre Dame vs. BYU Prediction, Pick and Preview

No. 18 Oklahoma State at No. 20 Houston

Saturday, 7:30 p.m. ET | FOX

One of the biggest games in the Big 12 Championship race takes place in Houston. Oklahoma State remains undefeated in conference play behind one of the Big 12’s best passing attacks, while Houston has emerged as one of the surprise contenders in the league.

Something has to give Saturday night.

Oklahoma State vs. Houston Prediction, Pick and Preview

No. 11 Utah at Colorado

Saturday, 10:15 p.m. ET | ESPN

Week 7 wraps up in Boulder, where undefeated Utah is a heavy favorite against Colorado. The Utes have been one of the most complete teams in the Big 12, but the Buffaloes are coming off a bye, playing at home and getting more than two touchdowns.

Could this one be closer than expected?

Utah vs. Colorado Prediction, Pick and Preview

Week 7 should tell us plenty about where the Big 12 race is headed. BYU has an opportunity to make a national statement, Oklahoma State and Houston meet in a game with major conference championship implications, while Texas Tech and Utah look to remain unbeaten.

By Saturday night, we should have an even clearer picture of the Big 12 contenders — and pretenders.

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